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Asset / Drug

Olaparib

Drug and asset intelligence for Olaparib with 10 indexed intelligence signals across regulatory, clinical, competitive, and market developments.

Signals
6
Catalysts
4
Stage
Development stage unavailable

Sponsor company

AstraZeneca →

Mechanism of action

Combination Therapy

Recent signals(6)

ClinicalAugust 2, 2026

Phase I/II Trial of Olaparib and Radium-223 in Advanced Prostate Cancer

This trial is investigating the safety and efficacy of olaparib in combination with radium-223 for patients with metastatic castration-resistant prostate cancer.

ClinicalJuly 30, 2026

Phase Ib/II Trial of Olaparib with AZD2014 or AZD5363 in Recurrent Endometrial and Ovarian Cancer

This trial evaluates the safety and optimal dosing of olaparib in combination with either vistusertib or capivasertib for recurrent cancers.

Clinical
June 24, 2026

Olaparib Investigated as Neoadjuvant Treatment in Ovarian Cancer Study

A study is underway to evaluate olaparib as a neoadjuvant treatment for patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer.

ClinicalJune 23, 2026

Phase II Trial of Olaparib and Pembrolizumab in Advanced Uveal Melanoma Initiated

A phase II trial is underway to evaluate the combination of olaparib and pembrolizumab in patients with advanced uveal melanoma.

ClinicalJune 18, 2026

Phase II Trial of Olaparib and Durvalumab Combinations in Recurrent Endometrial Cancer

A phase II trial is evaluating the efficacy of combinations of olaparib, durvalumab, cediranib, and capivasertib in recurrent or refractory endometrial cancer.

ClinicalJune 17, 2026

Polyploid Giant Cancer Cells Drive Aggressiveness in Ovarian Cancer and Indicate Poor Prognosis

Polyploid giant cancer cells (PGCCs) contribute to therapy resistance and poor prognosis in ovarian cancer.

Upcoming milestones

No catalysts indexed for this entity yet.

Related catalysts(4)

Topline Data

— Olaparib

June 24, 2026 · N/A

Topline Data

Merck — Olaparib

June 23, 2026 · N/A

Topline Data

AstraZeneca — Olaparib

June 18, 2026 · N/A

Topline Data

Bristol Myers Squibb — Olaparib

June 17, 2026 · N/A

Indications

Endometrial Cancer →
Ovarian Cancer →
Prostate Cancer →
Uveal Melanoma →

Therapeutic areas

Combination Therapy →
Endometrial Cancer →
Oncology →
Oncology · Endometrial Cancer →
Oncology · Ovarian Cancer →
Oncology · PARP Inhibitor →
Oncology · Uveal Melanoma →
Ovarian Cancer →
PARP Inhibitor →
Prostate Cancer →
Uveal Melanoma →

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