Clinical
Follow pivotal data releases and trial developments that create new strategic pressure for biotech and pharma operators.
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CLINICAL
A Phase II single-arm study is underway to evaluate the efficacy and safety of alpelisib in patients with PROS.
CLINICAL
A phase II trial is investigating adaptive radiation planning to minimize side effects in patients with stage II-IV non-small cell lung cancer.
COMPETITIVE
Contineum Therapeutics has initiated Phase 2 trial to assess PIPE-791 in patients with Idiopathic Pulmonary Fibrosis.
CLINICAL
The study aims to evaluate the upregulation of PD-L1 expression in peritoneal metastases from gastric cancer following HIPEC treatment.
CLINICAL
A phase II trial is underway to evaluate the efficacy of nivolumab alone or in combination with cabozantinib in preventing mucosal melanoma recurrence post-surgery.
CLINICAL
A phase II/III trial is evaluating the efficacy of atezolizumab combined with standard chemotherapy in advanced or metastatic neuroendocrine carcinomas originating outside the lung.
CLINICAL
A phase II trial is investigating the combination of cabazitaxel, carboplatin, and cetrelimab followed by niraparib in patients with metastatic aggressive variant prostate cancer.
CLINICAL
This phase II trial compares the efficacy of nivolumab combined with blinatumomab versus blinatumomab alone in relapsed B-ALL patients.
CLINICAL
A phase II trial is underway testing nivolumab and ipilimumab combined with sirolimus and prednisone in kidney transplant recipients with unresectable or metastatic skin cancer.
CLINICAL
A Phase 2 study is evaluating poziotinib's efficacy and safety in NSCLC patients with specific mutations.
CLINICAL
A phase II trial is investigating the efficacy of ibrutinib and rituximab in treating relapsed or refractory mantle cell lymphoma.
CLINICAL
A phase II/III trial is evaluating the efficacy of haloperidol and lorazepam in managing persistent agitated delirium in advanced cancer patients receiving palliative care.
CLINICAL
A Phase II/III trial has been initiated to evaluate BL-B01D1 combined with osimertinib in patients with resectable EGFR-mutant non-small cell lung cancer.
CLINICAL
A randomized phase II trial is evaluating the efficacy of paclitaxel with or without cixutumumab in metastatic esophageal cancer.
CLINICAL
The High-Altitude Neurodegeneration Cohort study aims to validate the link between chronic hypoxia and multiple system atrophy (MSA) risk in a large cohort of Han Chinese participants.
CLINICAL
A phase II trial is testing the addition of chemotherapy or chemo-immunotherapy to standard salvage surgery for PD-L1 positive head and neck squamous cell carcinoma.
CLINICAL
A phase II clinical trial is underway to evaluate the efficacy and safety of BL-B01D1 in combination with PD-1 monoclonal antibody.
CLINICAL
A Phase 2 study is underway to evaluate the efficacy of mosunetuzumab in CLL patients with detectable disease after BTKi treatment.
CLINICAL
A Phase II trial is investigating narlumosbart, RANKL-targeting mAb, combined with SBRT and first-line chemotherapy/immunotherapy in NSCLC patients with bone metastases.
CLINICAL
A phase 2 pilot study is comparing 124 I-PET/CT dosimetry methods in patients with high-risk differentiated thyroid cancer.
CLINICAL
The study aims to establish recommended Phase 2 doses for JNJ-79635322 in combination with daratumumab and other agents.
CLINICAL
A Phase 2 study is underway to assess the safety and optimal administration of JNJ-89402638 in mCRC and mGAC patients.
CLINICAL
A Phase 2 trial is underway to evaluate the efficacy of zanzalintinib monotherapy in patients with advanced or metastatic bone sarcomas.
CLINICAL
A Phase II trial is testing reduced adjuvant therapy for HER2+ breast cancer patients who achieved a pathologic complete response after neoadjuvant treatment.
COMPETITIVE
Rein Therapeutics is conducting Phase 2 trial of LTI-03, an inhaled medication for IPF, comparing it to placebo.
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