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ClinicalGastroenterologyInflammatory Bowel DiseaseTrial Update

Pilot Study on Non-Invasive Vagus Nerve Stimulation in IBD Remission

The VIBRANT-IBD study explores a novel therapeutic approach for managing inflammatory bowel disease (IBD) through non-invasive vagus nerve stimulation. Successful outcomes could reshape treatment paradigms and influence portfolio strategies for companies focused on IBD therapies.

Published: June 21, 2026
Updated: June 21, 2026
Author: Humanexa Intelligence
Therapeutic area: Gastroenterology / Inflammatory Bowel Disease
Asset: Nurosym
Indication: Crohn's disease therapies
Trial SummaryCLN

Phase III

Crohn's disease therapies

Status

Active

Signal Score

8.2

Signal assessment

Signal strength

high

Confidence level

moderate

Signalhigh
Confidencemoderate

Strategic implication

The VIBRANT-IBD study explores a novel therapeutic approach for managing inflammatory bowel disease (IBD) through non-invasive vagus nerve stimulation. Successful outcomes could reshape treatment paradigms and influence portfolio strategies for companies focused on IBD therapies.

Why it matters

The VIBRANT-IBD study explores a novel therapeutic approach for managing inflammatory bowel disease (IBD) through non-invasive vagus nerve stimulation. Successful outcomes could reshape treatment paradigms and influence portfolio strategies for companies focused on IBD therapies.

What changed

Trial Update

Analysis

The VIBRANT-IBD study is assessing the feasibility of non-invasive vagus nerve stimulation in IBD patients in remission.

The VIBRANT-IBD study explores a novel therapeutic approach for managing inflammatory bowel disease (IBD) through non-invasive vagus nerve stimulation. Successful outcomes could reshape treatment paradigms and influence portfolio strategies for companies focused on IBD therapies.

Monitor results from the MRI assessments and psychological questionnaires, as well as participant feedback on the intervention.

Related companies & assets

Assets

  • Nurosym →
  • ulcerative colitis therapies →

Sources & Humanexa intelligence

Source links

  • Pilot Study on Non-Invasive Vagus Nerve Stimulation in IBD Remission ↗

Related Humanexa pages

  • Pilot Study on Non-Invasive Vagus Nerve Stimulation in IBD Remission →

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Trial SummaryCLN

Phase III

Gastroenterology / Ulcerative Colitis

Status

Active

Sponsor

Eli Lilly

Signal Score

8.2

Clinicalhigh signal

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Trial SummaryCLN

Phase III

Neurology / Multiple System Atrophy

Status

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Sponsor

Teva

Signal Score

8.2

Clinicalhigh signal

Teva's TEV-56286 Trial for Multiple System Atrophy Underway

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