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Therapeutic Area

CAR T-cell Therapy

Therapeutic area intelligence for CAR T-cell Therapy with 19 indexed intelligence signals across regulatory, clinical, competitive, and market developments.

Signals
19
Catalysts
0
Companies
3

Companies

AstraZeneca →
B-ALL →
TSLPR-CART →

Assets

Anakinra →
AZD0120 →
Janssen →
NCI →
Phase →

Recent signals(19)

ClinicalAugust 17, 2026

Study on Anakinra to Reduce Cytokine Release Syndrome in B-ALL CAR T-Cell Therapy

ClinicalAugust 15, 2026

Phase I Trial of E-SYNC CAR T Cells for EGFRvIII Positive Glioblastoma

ClinicalAugust 11, 2026

Phase 1 Study of CD22-CAR TCell Immunotherapy for CD22+ Leukemia and Lymphoma Initiated

A Phase 1 study is underway to evaluate the safety and feasibility of CD22-CAR T-cell therapy for patients with CD22+ leukemia.

ClinicalAugust 7, 2026

Phase 1 Trial of CD19/BCMA CAR-γδT Cell Therapy in Autoimmune Diseases

A single-arm, dose-escalation trial is underway to assess the safety of allogeneic CD19/BCMA-targeted CAR-γδT cell therapy.

ClinicalAugust 6, 2026

Phase 1 Trial of TSLPR-CART in Refractory B-ALL Shows Promise for Targeting TSLPR Overexpression

A clinical trial is underway to evaluate TSLPR-CART therapy in adults with recurrent or refractory B-ALL characterized by TSLPR overexpression.

ClinicalAugust 1, 2026

Phase I Trial of EGFR/IL13Rα2 CAR T Cells for Recurrent High-Grade Gliomas

A phase I trial is investigating the safety and dosing of EGFR/IL13Rα2 pool-CAR T cells administered locoregionally for recurrent or progressive high-grade gliomas.

ClinicalJuly 31, 2026

Study on Long-term Effects of Pediatric CAR-T Cell Therapy Initiated

A prospective study is evaluating the short-term and long-term side effects of CAR-T cell therapy in pediatric patients.

CompetitiveJuly 27, 2026

Phase I/II Trial of CD20 CAR T-Cell Therapy for Relapsed/Refractory B Cell Lymphoma

A Phase I/II study is underway to evaluate the safety and efficacy of autologous T cells engineered to express CD20-specific CAR in patients with relapsed or refractory B cell non-Hodgkin lymphoma.

ClinicalJuly 25, 2026

NCI Trials B7-H3 CAR T Cell Therapy for Refractory Small Cell Lung Cancer

The National Cancer Institute is testing B7-H3 CAR T cell therapy in patients with refractory small cell lung cancer and extrapulmonary neuroendocrine cancer.

CompetitiveJuly 25, 2026

AstraZeneca Initiates Phase 1b/2 Trial of AZD0120 for Relapsed/Refractory Multiple Myeloma

AstraZeneca is conducting Phase 1b/2 trial of AZD0120, a dual CAR T-cell therapy targeting CD19 and BCMA, in patients with relapsed/refractory multiple myeloma.

CompetitiveJuly 22, 2026

CAR-T Cell Therapy for ALL: Emerging Research Trends and Focus Areas Identified

A bibliometric analysis reveals a significant growth in CAR-T cell therapy research for acute lymphoblastic leukemia, with a focus on long-term outcomes and risk assessment.

ClinicalJuly 15, 2026

Phase 1 Study of Allogeneic CD30.CAR-EBVSTs in Relapsed/Refractory Lymphomas

A clinical trial is investigating the safety and efficacy of allogeneic CD30.CAR-EBVSTs in patients with relapsed or refractory CD30-positive lymphomas.

ClinicalJuly 7, 2026

Phase 1b/2 Study of JNJ-90014496 for B-Cell Non-Hodgkin Lymphoma Initiated by Janssen

Janssen is conducting Phase 1b/2 study of prizloncabtagene autoleucel, CAR T-cell therapy targeting CD20 and CD19 in B-NHL.

ClinicalJuly 6, 2026

Phase I Trial of CD19/CD22 CAR T Cells in Pediatric B Cell Malignancies

A phase I trial is investigating the efficacy and safety of CD19/CD22 CAR T cells combined with chemotherapy in children and young adults with recurrent or refractory B acute lymphoblastic leukemia.

ClinicalJuly 5, 2026

Phase I Trial of CAR T Cells with Chlorotoxin for MMP2+ Recurrent Glioblastoma

A phase I trial is underway to evaluate CAR T cells targeting MMP2+ glioblastoma, focusing on safety and dosing.

ClinicalJuly 5, 2026

NCI Trials CD19/CD22 CAR T Cells for Refractory B Cell Malignancies in Young Patients

A clinical trial is underway testing a novel CD19/CD22 bicistronic CAR T-cell therapy for children and young adults with recurrent or refractory B cell malignancies.

ClinicalJuly 4, 2026

BrainChild Bio Initiates CAR T Therapy Study for DIPG Patients

BrainChild Bio is evaluating BCB-276, B7-H3-targeted CAR T cell therapy, in a clinical trial for DIPG patients.

ClinicalJuly 1, 2026

Phase 2 Trial of Lisocabtagene Maraleucel Targets Minimal Residual Disease in Large B-cell Lymphoma

A Phase 2 trial is underway to evaluate lisocabtagene maraleucel in preventing recurrence of large B-cell lymphoma in patients with minimal residual disease.

ClinicalJune 29, 2026

First-in-human Phase 1 Study of ML261 in R/R SCLC and NECs Initiated by Moonlight Bio

Moonlight Bio has initiated a first-in-human Phase 1 trial for ML261, targeting R/R SCLC and select NECs.

Upcoming catalysts

No catalysts indexed for this entity yet.

Indications

No related entities indexed yet.

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