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Therapeutic Area

Hepatology

Therapeutic area intelligence for Hepatology with 25 indexed intelligence signals across regulatory, clinical, competitive, and market developments.

Signals
25
Catalysts
0
Companies
7

Companies

AbbVie →
Akero Therapeutics →
Ausper Biopharma →
Boehringer Ingelheim →
Gilead →
Mirum Pharmaceuticals →
Roche →

Assets

AHB-171 →
Concerns →
Efruxifermin →
Guselkumab →
Hepatology →
HEPCLUDEX →
Ipsen →
Livmarli →
Mallinckrodt →
MASLD →
Novel →
Resmetirom →
Survodutide →
Tirzepatide →
Variceal Bleeding →
VIR-2218 →
Wedelolactone →
Wegovy →

Recent signals(25)

ClinicalAugust 6, 2026

Novel MRI Methods for Liver Disease Biomarkers Under Evaluation

A study is assessing new MRI techniques for quantifying blood perfusion and tissue microstructure in liver diseases.

ClinicalAugust 4, 2026

Study on Hepatic Lipid Metabolism in Alcohol Use Disorder Initiated

A clinical trial is underway to assess hepatic lipid metabolism in patients with alcohol use disorder through liver biopsies.

ClinicalAugust 3, 2026

Study on Guselkumab Therapy's Impact on NAFLD in PsA Patients

The study investigates the effects of Guselkumab on disease severity in PsA patients with NAFLD.

ClinicalJuly 28, 2026

Study on Timing of Withdrawal from Long-Term Antiviral Treatment for Chronic Hepatitis B

A study is underway to evaluate the safety and effectiveness of withdrawing antiviral treatment after 4 years in chronic hepatitis B patients.

RegulatoryJuly 24, 2026

Concerns Raised Over Hepatotoxicity of Epimedium brevicornu Maxim.

Epimedium brevicornu Maxim., traditionally considered non-toxic, is associated with increasing hepatobiliary toxicity.

ClinicalJuly 23, 2026

Mirum Pharmaceuticals Evaluates Livmarli in Long-Term Study for Alagille Syndrome and PFIC

Mirum Pharmaceuticals is conducting a long-term study to assess the safety and efficacy of Livmarli in patients with Alagille syndrome and PFIC.

RegulatoryJuly 20, 2026

FDA Grants Priority Review for BLA761468 (HEPCLUDEX) by Gilead Sciences

The FDA has granted priority review status for Gilead Sciences' BLA761468, known as HEPCLUDEX.

RegulatoryJuly 19, 2026

Resmetirom (Rezdiffra) Approved for MASH Treatment in Adults

Resmetirom (Rezdiffra) has been authorized for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) in adults.

ClinicalJuly 18, 2026

Ausper Biopharma initiates AHB-171 trial for chronic hepatitis B

Ausper Biopharma is conducting an open-label trial to assess the efficacy and safety of AHB-171 in chronic hepatitis B patients.

ClinicalJuly 14, 2026

Study Evaluates Outpatient Ultrasound for Early Diagnosis of Fatty Liver

A study by the Medical College of Wisconsin is assessing the effectiveness of outpatient ultrasound for diagnosing fatty liver.

ClinicalJuly 10, 2026

Ipsen initiates trial of Elafibranor for Primary Biliary Cholangitis in patients intolerant to UDCA

A new clinical trial is underway to evaluate the efficacy of Elafibranor in patients with Primary Biliary Cholangitis who have not responded adequately to Ursodeoxycholic Acid.

ClinicalJuly 9, 2026

4D Flow MRI Study Aims to Improve Risk Stratification for Variceal Bleeding in Cirrhosis

A study is underway to validate non-invasive MRI biomarkers for detecting gastroesophageal varices in cirrhosis patients.

ClinicalJuly 8, 2026

Study Compares Large Volume Paracentesis and TIPS for Ascites Relief

A clinical trial is underway comparing Large Volume Paracentesis with albumin infusion to early TIPS for treating ascites.

ClinicalJuly 5, 2026

Long-term Study on Odevixibat Effectiveness for PFIC in South Korea Initiated

A new study has been initiated in South Korea to evaluate the long-term effectiveness and safety of odevixibat in patients with PFIC.

RegulatoryJuly 4, 2026

Semaglutide (Wegovy) approved for metabolic-associated steatohepatitis treatment

Semaglutide injection has received approval for the treatment of metabolic-associated steatohepatitis in adults with moderate-to-advanced liver fibrosis.

ClinicalJuly 3, 2026

Ipsen initiates trial for elafibranor in Primary Sclerosing Cholangitis

Ipsen is conducting a trial to assess the efficacy and safety of elafibranor in adult patients with Primary Sclerosing Cholangitis.

ClinicalJuly 2, 2026

Exosome-based delivery of Wedelolactone shows promise for sepsis-induced liver injury

A novel exosome-based drug delivery system (Exo@WEL) enhances liver-targeting and hepatoprotection of Wedelolactone.

ClinicalJune 29, 2026

Akero Therapeutics Initiates Study of Efruxifermin in NASH/MASH Patients

Akero Therapeutics is conducting a multi-center, randomized, double-blind, placebo-controlled study of efruxifermin in patients with non-cirrhotic NASH/MASH and fibrosis.

ClinicalJune 27, 2026

Vir Biotechnology Initiates Phase 2 Trial for Chronic Hepatitis D with VIR-2218 and VIR-3434

Vir Biotechnology is conducting Phase 2 trial assessing the safety and efficacy of combination therapy with VIR-2218 and VIR-3434 for chronic hepatitis D infection.

ClinicalJune 25, 2026

Boehringer Ingelheim's Survodutide Trial for NASH/MASH with Cirrhosis Underway

Boehringer Ingelheim is conducting a trial to evaluate the efficacy of survodutide in adults with NASH or MASH and cirrhosis.

ClinicalJune 22, 2026

Tirzepatide Trial for Metabolic Alcohol-Associated Liver Disease in AUD Patients

A clinical trial is underway to evaluate the efficacy of Tirzepatide in patients with Alcohol Use Disorder and MetALD.

RegulatoryJune 21, 2026

FDA Accepts Supplemental NDA for Terlivaz by Mallinckrodt

The FDA has accepted a supplemental NDA for Terlivaz (terlipressin acetate) submitted by Mallinckrodt.

ClinicalJune 20, 2026

Novel Oral Nanoemulsion Targets Hepatic Stellate Cells in Liver Fibrosis Treatment

A vitamin A-functionalized self-nanoemulsifying drug delivery system effectively targets hepatic stellate cells in liver fibrosis.

CompetitiveJune 16, 2026

Roche Launches Liver Disease Panel to Enhance Chronic Liver Disease Management

Roche has launched the Liver Disease Panel, a suite of certified algorithms aimed at improving the management of chronic liver disease (CLD). This panel includes the LiverPRO algorithm, which facilitates early detection of liver fibrosis using routine blood markers.

ClinicalJune 11, 2026

Trial of CXD and Ketogenic Diet for MASLD Shows Structured Approach

A clinical trial is underway to evaluate the efficacy of CXD combined with a restrictive ketogenic diet in treating MASLD.

Upcoming catalysts

No catalysts indexed for this entity yet.

Indications

Alagille Syndrome →
Alcohol Use Disorder →
Chronic Hepatitis B →
Chronic Hepatitis D →
Chronic Liver Disease →
Fatty Liver Disease →
Liver Fibrosis →
Metabolic Dysfunction-Associated Steatohepatitis →
Psoriatic Arthritis →
Rare Disease →

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