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Indication

Hepatocellular Carcinoma

Clinical and regulatory intelligence for Hepatocellular Carcinoma with 17 indexed intelligence signals across regulatory, clinical, competitive, and market developments.

Signals
17
Catalysts
0
Assets
13

Relevant assets

cadonilimab →
CENPI →
Compound →
Durvalumab →
finotonlimab →
High-Intensity →
lenvatinib →
MAGED4 →
pembrolizumab →
QL1706 →
SHR-8068 →
sorafenib →
Zanthoxylum →

Relevant companies

Alnylam Pharmaceuticals →
AstraZeneca →
oncology pharmaceutical companies →
oncology therapeutics →
PD-L1 →

Recent signals(17)

ClinicalAugust 4, 2026

Study on mSEPT9 Biomarker for Early Detection of Hepatocellular Carcinoma in Cirrhosis Patients

A clinical trial is evaluating the mSEPT9 biomarker's ability to predict hepatocellular carcinoma in cirrhosis patients.

StrategyJuly 29, 2026

Finotonlimab plus bevacizumab unlikely cost-effective vs. sorafenib for HCC in China

Finotonlimab plus bevacizumab showed increased survival benefits but was not cost-effective compared to sorafenib.

ClinicalJuly 26, 2026

Zanthoxylum nitidum shows multi-target anti-HCC mechanisms via network pharmacology

The study identifies key genes and pathways involved in the anti-HCC mechanisms of Zanthoxylum nitidum, highlighting its potential clinical use.

ClinicalJuly 26, 2026

Compound Kushen Injection Inhibits Immune Evasion in Hepatocellular Carcinoma via PD-L1 O-GlcNAcylation

Compound Kushen Injection (CKI) inhibits glycolysis and immune evasion in HCC cells by reducing O-GlcNAcylation of PD-L1.

ClinicalJuly 19, 2026

Study on THIO and Cadonilimab for Resectable Hepatocellular Carcinoma Launched

A clinical trial is underway to evaluate the efficacy and safety of cadonilimab alone and in combination with ateganosine for treating resectable HCC.

ClinicalJuly 18, 2026

AstraZeneca's Study on Durvalumab and Tremelimumab in HCC with TACE

AstraZeneca is conducting a global study evaluating the combination of durvalumab, tremelimumab, and lenvatinib with TACE in patients with locoregional hepatocellular carcinoma.

ClinicalJuly 10, 2026

Phase 3 Trial of SHR-8068, Adebrelimab, and Bevacizumab in Hepatocellular Carcinoma

A Phase 3 clinical trial is underway to assess the combination of SHR-8068, Adebrelimab, and Bevacizumab with TACE in patients with incurable hepatocellular carcinoma.

ClinicalJuly 9, 2026

Phase 2b Study of JX-594 in Advanced Liver Cancer Patients Failing Sorafenib

A Phase 2b study is evaluating the efficacy of JX-594 (Pexa-Vec) combined with best supportive care in advanced HCC patients who have not responded to sorafenib.

ClinicalJuly 5, 2026

CENPI identified as a promoter of hepatocellular carcinoma progression via PI3K/AKT/mTOR pathway

CENPI is linked to hepatocellular carcinoma progression through activation of the PI3K/AKT/mTOR-CDK2 cascade.

ClinicalJuly 4, 2026

SHR-8068 Trial in Resectable Hepatocellular Carcinoma Shows Promise

A trial is evaluating SHR-8068 combined with Adebrelimab and Apatinib for resectable hepatocellular carcinoma.

ClinicalJune 28, 2026

ABHD17C identified as a regulator of lenvatinib efficacy in hepatocellular carcinoma

The study investigates the role of ABHD17C in modulating the efficacy of lenvatinib for HCC treatment.

ClinicalJune 26, 2026

SBRT Combined with QL1706 Shows Promise in Second-Line Hepatocellular Carcinoma Therapy

A clinical trial is underway to evaluate the efficacy and safety of SBRT plus QL1706 in patients with hepatocellular carcinoma after prior systemic therapy.

ClinicalJune 21, 2026

Dual-ligand cantharidin nanoparticles show promise for hepatocellular carcinoma treatment

Dual-ligand-modified cantharidin nanoparticles demonstrated a 58.67% tumor inhibition rate in Huh-7 tumor-bearing mice, with enhanced safety profiles.

ClinicalJune 21, 2026

Alnylam's ALN-BCAT Study in Hepatocellular Carcinoma Evaluates Safety and Efficacy

Alnylam Pharmaceuticals is conducting a study to evaluate the safety and antitumor activity of ALN-BCAT, both alone and in combination with pembrolizumab, in patients with hepatocellular carcinoma.

ClinicalJune 20, 2026

High-Intensity Thermal Stress Boosts NK-Cell Cytotoxicity in HCC

High-intensity thermal stress enhances the cytotoxicity of NK-cells in poorly differentiated hepatocellular carcinoma.

ClinicalJune 20, 2026

MAGED4 promotes HCC progression via JAK2/STAT3 pathway activation

MAGED4 is upregulated in hepatocellular carcinoma and promotes tumor progression by activating the JAK2/STAT3 pathway.

ClinicalJune 17, 2026

Study on Durvalumab, Bevacizumab, and TACE for Advanced Hepatocellular Carcinoma

A clinical trial is evaluating the combination of durvalumab, bevacizumab, and TACE for advanced HCC, focusing on 6-month progression-free survival.

Upcoming catalysts

No catalysts indexed for this entity yet.

Therapeutic areas

Hepatocellular Carcinoma →
Oncology →

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